• br Practical management of perioperative anticoagulation and

  2019-06-11

  

  Practical management of perioperative anticoagulation and antiplatelet therapy in CIED surgery By integrating the current literature and the experience from our own practice, we developed a practical algorithm recently to guide the perioperative management of anticoagulation and antiplatelet ther

• GP ablation has been regarded as a vagal denervation procedu

  2019-06-11

  

  GP ablation has been regarded as a vagal denervation procedure that reduces the vagal tone in the atria and the vulnerability to AF. However, it is unclear how much vagal effect on the atrium is attenuated and how much of the atrium is denervated after the ablation. According to the GP mapping by Mc

• Introduction Bone is a very dynamic

  2019-06-11

  

  Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components

• La no intervenci n en los

  2019-06-10

  

  La no intervención en los asuntos de otro Estado no significa indiferencia ante los problemas que éste pueda tener. En efecto, algunos usos y gestiones pueden perjudicar bet inhibitor países vecinos y también al mismo Estado que las realiza. Es por esto que la soberanía no resulta absoluta en lo que

• En una clara cr tica

  2019-06-10

  

  En una clara crítica al modelo neoliberal gay importado de Estados Unidos, Néstor Perlongher sostiene que “el gay pasa orthopoxvirus variola tomarse como modelo de conducta. Este operativo de normalización arroja a los bordes a los nuevos marginados, los excluidos de la fiesta: travestis, locas, cho

• br Disclosures br Acknowledgments This study was supported b

  2019-06-10

  

  Disclosures Acknowledgments This study was supported by the Austrian National Science Fund (FWF), Grant # SFB-F4704. Introduction Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Extramedullary involvement of the kidneys is seen in around 7% when assessed by in

• br Discussion Chronic myelogenous leukemia

  2019-06-10

  

  Discussion Chronic myelogenous leukemia (CML) is a clonal disorder involving the pluripotent stem cell and is consistently associated with the BCR-ABL1 fusion gene located on the Philadelphia chromosome [1]. The disease typically evolves in 3 distinct clinical stages: chronic and accelerated phas

• solution calculator For example glutamate is increasingly re

  2019-06-10

  

  For example, glutamate is increasingly recognized as one of the important dysregulated signaling molecules in cancer biology, especially in the context of bone metastasis. Commonly recognized as an excitatory neurotransmitter necessary for normal solution calculator function, glutamate is also inti

• The presence of an inflammatory infiltrate is associated

  2019-06-10

  

  The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha

• The authors of the NCCN

  2019-06-10

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• EVP-6124 Roughly years have gone by since the identification

  2019-06-10

  

  Roughly 15 years have gone by since the identification of the main characters involved in the interplay of the RANK–RANKL system. This gave rise to the race for elucidating their biological role . In those years, in vivo silencing experiments for both Receptor Activator of Nuclear Factor κ B (RANK)

• X rays commonly show a

  2019-06-10

  

  X-rays commonly show a typical licked candy stick appearance, based on concentric bone resorption. Common blood tests are usually normal, but bone alkaline phosphatase (BAP) may be elevated if a fracture occurred [8]. GSD is a diagnosis of exclusion. Diseases responsible of bone osteolysis such as i

• Cisplatin based chemotherapy is commonly used

  2019-06-06

  

  Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo

• br Sebastian Vollmer and colleagues April conclude that the

  2019-06-06

  

  Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the Senexin B in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called trickle-down approach of a

• In patients with typical atrial

  2019-06-06

  

  In patients with typical atrial flutter circulating around the tricuspid valve, the verification of a bidirectional conduction block is recommended for cavotricuspid isthmus (CTI) ablation, because a unidirectional conduction block at the CTI has been previously reported to cause recurrence of atria

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