• A previous study from our group

  2019-07-01

  

  A previous study from our group demonstrated that the truncated form of OPG (1-194) has greater activity than the complete form, given that proteoglycans present in the bone tumor microenvironment may bind to full length OPG, thereby limiting its bioavailability and bioactivity [31]. Therefore the t

• Phosphorus is essential for organic activity such as cellula

  2019-07-01

  

  Phosphorus is essential for organic activity such as cellular signal transduction, membrane transport, mineral metabolism, and 9-amino Camptothecin exchange [1]. Bone and teeth store 80% of the total body phosphorus. Intracellular phosphorus consists of the form of organic compounds such as adenosi

• thapsigargin br Case report A year

  2019-07-01

  

  Case report A 56-year-old man with a history of prior myocardial infarction and severe left ventricular dysfunction underwent an implantable cardioverter defibrillator (ICD) thapsigargin for primary prevention of sudden cardiac death. Since the patient had normal sinus rhythm and normal atrio-ve

• Preamble The J wave syndromes JWSs

  2019-07-01

  

  Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology Prostaglandin E2 over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1

• br En el contexto argentino comprendido entre las d cadas

  2019-07-01

  

  En el contexto argentino comprendido entre las décadas del treinta y del cincuenta, la legitimación del elemento indígena —en su diálogo con los sustratos hispano-colonial e inmigratorio— es emprendida por muy pocos intelectuales provenientes del campo del ensayismo de interpretación nacional. Baj

• A possible mechanism of the initiation of HSTCL is

  2019-07-01

  

  A possible mechanism of the Ferrostatin-1 structure of HSTCL is a prolonged immunosuppressive status which generates the expansion of γδ T-cells recognizing multiple pathogens through excessive antigenic stimulation. Our cases did not have any previous illness related to immunosuppression, recurren

• br Discussion Case reports of successful chemotherapy desens

  2019-07-01

  

  Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,

• By showing the great variability in

  2019-06-29

  

  By showing the great variability in surgical outcomes across LMICs, Uribe-Leitz and colleagues have shared with the world instructive knowledge that aids our ongoing advocacy efforts to promote quality in surgical care in resource-limited settings. Ultimately, for destitute sick and injured patients

• br Conclusions br Conflict of interest br Introduction Radio

  2019-06-29

  

  Conclusions Conflict of interest Introduction Radiofrequency (RF) catheter ablation is an established method of therapy for symptomatic supraventricular tachycardia (SVT). It has gained widespread acceptance for the treatment of accessory pathways in pediatric SVTs [1]. Accessory pathways a

• Inappropriate shocks can be avoided

  2019-06-29

  

  Inappropriate shocks can be avoided in the following ways while using a monitoring zone: (1) not setting a monitoring zone; (2) setting the VT zone at a higher rate than that of sinus tachycardia; (3) setting the VF zone at a higher rate for evaluating PAC intervals; (4) increasing the VF detection

• Curative treatments which include surgical resection

  2019-06-29

  

  Curative treatments, which include surgical resection, percutaneous ablation and liver transplantation, were considered as the optimal treatment for patients with very early/early stage HCC by BCLC criteria. Furthermore, advances in liver surgery make the resection of large and/or multifocal HCC pos

• br Authors disclosure Mark Clemons received honoraria for

  2019-06-29

  

  Authors\' disclosure Mark Clemons received honoraria for talks from Novartis and Amgen, research funding from Novartis. Case In September 2007 a 9½-year-old boy was diagnosed with a Ewing sarcoma (EWS-FL1 translocation positive) of the right scapula. MRI showed a tumor of 8.0×2.9 ×6.2cm locat

• Numerous animal studies have demonstrated beyond doubt

  2019-06-29

  

  Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit

• br Point of care diagnostic

  2019-06-29

  

  Point-of-care diagnostic tests (POCTs) can enable health-care workers to provide more rapid and effective care to people in low-resource settings. POCTs should ideally meet the WHO\'s ASSURED criteria—ie, being affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and d

• Seg n el coeficiente de Gini que mide la

  2019-06-29

  

  Según el coeficiente de Gini que mide la desigualdad, en la región es de 0.51, nivel de desigualdad sustancialmente más alto que otras zonas del mundo, al tener en cuenta que Estados Unidos tiene 0.378 y los países de la ocde 0.313. De ahí que el promedio simple de los valores en América Latina indi

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